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The outcome suggested that a transient and limited increase in gut permeability compared with the unregulated breach of the gut barrier function due to the TJ deregulation and epithelial cell apoptosis can rather lead to a dominant regulatory immune response to gut microbiota antigens and to a net anti-inflammatory effect

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While, during activation, some amino acids are actively regulated within the DCs to meet the following functional requirements: increasing biosynthesis to drive the production of effector molecules (154)